Melittin, Free acid
Product Information
| Cas No. | 123168-46-7 |
| Puriy | ≥95% |
| Molucular Weight | 2847 |
| Formula | C131H228N38O32 |
| InChIKey | APGXIPWPUMTZGN-CTOWXMLOSA-N |
| Sequence (Short) | GIGAVLKVLTTGLPALISWIKRKRQ |
| Sequence | Gly-Ile-Gly-Ala-Val-Leu-Lys-Val-Leu-Thr-Thr-Gly-Leu-Pro-Ala-Leu-Ile-Ser-Trp-Ile-Lys-Arg-Lys-Arg-Gln-OH |
| Description | Melittin free acid is a basic 26-amino-acid polypeptide, the major active ingredient of honeybee venom. Melittin free acid is an activator of phospholipase A2 (PLA2). Melittin free acid has broad-spectrum antifungal activity with MIC values of 0.4-60 μM. Melittin free acid hinders fungal growth by inducing cell apoptosis, repressing (1,3)-β-D-glucan synthase and participating in other pathways. |
| Target | Fungal; Apoptosis Phospholipase Reactive Oxygen Species |
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