N(p-Tosyl)-GPR-pNA

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Substrate
N(p-Tosyl)-GPR-pNA
N(p-Tosyl)-GPR-pNA
Cat.No.CP2221010
Size10 mg
Quantity
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Product Information
Cas No.86890-95-1
Puriy≥95%
Molucular Weight602
FormulaC26H34N8O7S
InChIKeyNGXDRWVTRQRSED-VROPFNGYSA-N
Sequence (Short)N-(p-Tosyl)-GPR-pNA
SequenceN(p-Tosyl)-Gly-Pro-Arg-pNA
DescriptionN-(p-Tosyl)-GPR-pNA acetate (Chromozym-TH) is a chromogenic substrate targeting the synthetic peptides Hirunorm IV and Hirunorm V and can be used to detect the dissociation constants (KI) of both peptides. Hirunorm IV and Hirunorm V are reversible inhibitors of amidolytic thrombin activity. By varying the peptide concentration at a fixed concentration of the chromogenic substrate N-(p-Tosyl)-GPR-pNA acetate, the dissociation constants determined were 0.134 nM (Hirunorm IV) and 0.245 nM (Hirunorm V).
TargetFluorescent Dye
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