N(p-Tosyl)-GPR-pNA
Product Information
| Cas No. | 86890-95-1 |
| Puriy | ≥95% |
| Molucular Weight | 602 |
| Formula | C26H34N8O7S |
| InChIKey | NGXDRWVTRQRSED-VROPFNGYSA-N |
| Sequence (Short) | N-(p-Tosyl)-GPR-pNA |
| Sequence | N(p-Tosyl)-Gly-Pro-Arg-pNA |
| Description | N-(p-Tosyl)-GPR-pNA acetate (Chromozym-TH) is a chromogenic substrate targeting the synthetic peptides Hirunorm IV and Hirunorm V and can be used to detect the dissociation constants (KI) of both peptides. Hirunorm IV and Hirunorm V are reversible inhibitors of amidolytic thrombin activity. By varying the peptide concentration at a fixed concentration of the chromogenic substrate N-(p-Tosyl)-GPR-pNA acetate, the dissociation constants determined were 0.134 nM (Hirunorm IV) and 0.245 nM (Hirunorm V). |
| Target | Fluorescent Dye |
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