Amylin,human
Product Information
| Cas No. | 122384-88-7 |
| Puriy | ≥95% |
| Molucular Weight | 3903 |
| Formula | C165H261N51O55S2 |
| InChIKey | PLOPBXQQPZYQFA-AXPWDRQUSA-N |
| Sequence (Short) | KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY-NH2(Disulfide bridge:Cys2-Cys7) |
| Sequence | Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Ala-Ile-Leu-Ser-Ser-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2(Disulfide bridge:Cys2-Cys7) |
| Description | Endogenous peptide. Potent amylin, calcitonin (EC50 = 0.67 nM), CGRP and adrenomedullin receptor agonist. Potently inhibits insulin-stimulated glucose uptake in skeletal muscle cells (IC50 = 12 pM). Implicated in type II diabetes. Active in vivo. Rat (ab142399) and feline (ab142397) amylin also available. |
| Target | Amylin Receptor |
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