Calcium-Like Peptide
Product Information
| Cas No. | 145224-99-3 |
| Puriy | ≥95% |
| Molucular Weight | 842 |
| Formula | C40H75N9O10 |
| InChIKey | HTOHLCKNMRKYLK-KVZSNLRASA-N |
| Sequence (Short) | VAITVLVK |
| Sequence | Val-Ala-Ile-Thr-Val-Leu-Val-Lys |
| Description | CALP1 is a calmodulin (CaM) agonist (Kd of 88 µM) with binding to the CaM EF-hand/Ca2+-binding site. CALP1 blocks calcium influx and apoptosis (IC50 of 44.78 µM) through inhibition of calcium channel opening. CALP1 blocks glutamate receptor channels and blocks a store-operated nonselective cation channel. CALP1 activates CaM-dependent phosphodiesterase activity. |
| Target | mGluR; Phosphodiesterase (PDE); Apoptosis; Calmodulin |
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