Ac-Choline Receptor α1(129-145)
Product Information
| Cas No. | 194737-11-6 |
| Puriy | ≥95% |
| Molucular Weight | 2038 |
| Formula | C90H136N22O28S2 |
| InChIKey | HLWBRNDODNBUQE-OYAPUHASSA-N |
| Sequence (Short) | EIIVTHFPFDEQNCSMK |
| Sequence | Glu-Ile-Ile-Val-Thr-His-Phe-Pro-Phe-Asp-Glu-Gln-Asn-Cys-Ser-Met-Lys |
| Description | This fragment of a conserved sequence in nicotinic acetylcholine receptor activates T helper lymphocytes and induces the production of autoantibodies that cause electrophysiologic signs of experimental autoimmune myasthenia gravis. EIIVTHFPFDEQNCSMK may be useful in the development of a peptide-based antigen-specific immunotherapy of myasthenia gravis. |
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