RGD-4C
Product Information
| Cas No. | 332179-76-7 |
| Puriy | ≥95% |
| Molucular Weight | 1145 |
| Formula | C42H60N14O16S4 |
| Solubility in DMSO | 25 mg/mL |
| InChIKey | WQLVAVHKXVRFPP-AVWCAVILSA-N |
| Sequence (Short) | ACDCRGDCFCG(Disulfide bridge: Cys2-Cys10; Cys4-Cys8) |
| Sequence | Ala-Cys-Asp-Cys-Arg-Gly-Asp-Cys-Phe-Cys-Gly(Disulfide bridge:Cys2-Cys10, Cys4-Cys8) |
| Description | RGD-4C is a arginine-glycine-aspartic acid peptide (ACDCRGDCFC) with integrin binding activity. The Arg-Gly-Asp (RGD) sequence serves as the primary integrin recognition site in extracellular matrix proteins, and peptides containing this sequence can mimic the recognition specificity of the matrix proteins. RGD-4C is a αv-integrin ligand, can conjugate with bioactive molecule to exert antitumor effects in animal models. |
| Target | Integrin |
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