(Pyr5,N-Me-Phe8,Sar9)-Substance P (5-11)
Product Information
| Cas No. | 77128-69-9 |
| Puriy | ≥95% |
| Molucular Weight | 880 |
| Formula | C43H61N9O9S |
| InChIKey | IEEBRBMEXFNVKU-CVUOCSEZSA-N |
| Sequence (Short) | {Pyr}-QF(-Me)F-Sar-LM-NH2 |
| Sequence | Pyr-Gln-Phe-N-Me-Phe-Sar-Leu-Met-NH2|Pyr-Gln-Phe-N-Me-Phe-Sar-Leu-Met-NH2 |
| Description | (Pyr5,N-Me-Phe8,Sar9)-Substance P (5-11) is a Substance P (HY-P0201) analogue that has approximately the same effects as Substance P (HY-P0201) on neurokinin 1 receptor (NK1R) in rat brain, but with a much longer duration of action. (Pyr5,N-Me-Phe8,Sar9)-Substance P (5-11) selectively activates dopamine metabolism in the mesencephalon and midbrain cortex of the rat brain.(Pyr5,N-Me-Phe8,Sar9)-Substance P (5-11) also increases motor activity and induces recovery of addictive agent-seeking behavior in rats. |
| Target | Neurokinin Receptor |
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