Leu-Valorphin-Arg

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Valorphin
Leu-Valorphin-Arg
Leu-Valorphin-Arg
Cat.No.CP2399005
Size5 mg
Quantity
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Product Information
Cas No.135861-77-7
Puriy≥95%
Molucular Weight1161
FormulaC56H84N14O13
InChIKeyTYDMAYCCXBUMFX-ZAIVSCQOSA-N
Sequence (Short)LVVYPWTQR
SequenceLeu-Val-Val-Tyr-Pro-Trp-Thr-Gln-Arg
DescriptionLeu-Valorphin-Arg, LVVYPWTQR, corresponds to the sequence (32-40) of the β-,δ-,γ-, and ε-chains of human hemoglobin. It shows binding affinity for µ- and sigma-opioid receptors and has opioid activity in the GPI bioassay. LVV-Hemorphin-6 is found in large amounts in the pituitary and seems to be present in the circulation to a much lesser degree. In view of its high stability towards the membrane-bound lung enzymes and its strong inhibitory action on ACE activity, LVV-hemorphin-6 appears to be the most potent of the hemorphin-related peptides assayed.
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