Leu-Valorphin-Arg
Product Information
| Cas No. | 135861-77-7 |
| Puriy | ≥95% |
| Molucular Weight | 1161 |
| Formula | C56H84N14O13 |
| InChIKey | TYDMAYCCXBUMFX-ZAIVSCQOSA-N |
| Sequence (Short) | LVVYPWTQR |
| Sequence | Leu-Val-Val-Tyr-Pro-Trp-Thr-Gln-Arg |
| Description | Leu-Valorphin-Arg, LVVYPWTQR, corresponds to the sequence (32-40) of the β-,δ-,γ-, and ε-chains of human hemoglobin. It shows binding affinity for µ- and sigma-opioid receptors and has opioid activity in the GPI bioassay. LVV-Hemorphin-6 is found in large amounts in the pituitary and seems to be present in the circulation to a much lesser degree. In view of its high stability towards the membrane-bound lung enzymes and its strong inhibitory action on ACE activity, LVV-hemorphin-6 appears to be the most potent of the hemorphin-related peptides assayed. |
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