The purity of synthetic peptides is a critical factor that directly influences the reproducibility and reliability of your experimental outcomes. Whether for basic research, diagnostics, or therapeutic development, low-quality peptides can lead to inconsistent results, off-target effects, and wasted resources. At GenCefe Biotech, we prioritize high-purity peptides and comprehensive quality control (QC) throughout the synthesis process.
Why Peptide Purity Matters:
● Research reproducibility: Impure peptides may contain truncated sequences or side-products that affect biological assays.
● Assay specificity: Contaminants can interfere with target binding, enzymatic reactions, or cellular uptake.
● Therapeutic applications: Regulatory requirements demand rigorous purity for clinical-grade peptides.
How Purity Is Measured:
● High-Performance Liquid Chromatography (HPLC): Used to quantify purity and identify impurities based on retention times and peak integration.
● Mass Spectrometry (MS): Confirms the molecular weight and integrity of the synthesized peptide.
● Capillary Electrophoresis (CE): Offers high-resolution separation of charged peptide species.
Common Purity Grades:
● Crude: –50–70% (for initial screening)
● Desalted: -70–85%
● 90%: Suitable for in vitro assays
● 95%: Required for in vivo research or diagnostic use
● 98%: Pharmaceutical/clinical grade
GenCefe’s Quality Assurance Process: Our QC protocols include:
● Real-time monitoring during synthesis
● HPLC and MS analysis of every batch
● Custom documentation and COA
● Optional endotoxin and microbial testing for high-grade peptides
Customization and Transparency: Customers can request specific purity levels and analytical data. We provide complete transparency in reporting, helping you make informed decisions for your project.
Conclusion:
Peptide purity isn't a luxury—it's a necessity. GenCefe ensures your peptides meet the highest standards through a blend of advanced technology and expert oversight.
Need Custom Peptides ? Contact Us Today
For inquiries or quotations, reach out to our peptide experts at [email protected] . GenCefe Biotech—your trusted partner in peptide synthesis and modification .
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