The nucleic acid drug is a therapy that regulates the after-gene transcription and prior-protein translation stage, acting upstream of protein synthesis. Because of its advantages of simple design, short development cycle, strong target specificity, a wide range of therapeutic fields, and long-term effects, it is expected to become a new generation of drugs after small molecule drugs and antibody drugs. Oligonucleotide drugs mainly include antisense nucleic acid (ASOs), siRNA, miRNA, nucleic acid aptamer (Aptamer) and sgRNA, transfer RNA (tRNA) fragments, etc.

GenCefe Biotech has established a complete oligonucleotide synthesis and analysis technology platform. We provide nucleic acid drug researchers with a one-stop solution for oligonucleotide from design, synthesis, modification, and screening to early-stage drug efficacy, pharmacokinetics, and toxicology research. Our services include custom synthesis of various high-quality single-stranded and double-stranded RNA, DNA, DNA-RNA chimera oligonucleotides, and conjugates of oligonucleotides with GalNAc, polypeptides, and other molecules. The synthesis scale ranges from OD to gram, decagram, and hectogram levels, and the products are purified by HPLC, which can meet the requirements of cell level, animal experiments, and preclinical research.

Overall Solution

Service Features

• Experienced R&D and production teams, mature oligonucleotide synthesis, and modification technology platforms. We can provide up to 100-gram scale oligonucleotide synthesis with batch-to-batch consistency;

• Professional technical support and project management team, standardized project management process, perfect pre-sales, and after-sales service

• Strict quality control standards, ISO9001 quality management system. A variety of customized QC items are available upon request besides the standard QC items.

• The overall solution for oligonucleotide from design, synthesis, modification, and screening to early-stage drug efficacy, pharmacokinetics, and toxicology research.

Capacity & Capability

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